James Appleman: search on Z-Library

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1

AMP Deaminase Inhibitors. 3. SAR of 3-(Carboxyarylalkyl)coformycin Aglycon Analogues

Kasibhatla, Srinivas Rao, Bookser, Brett C., Probst, Gary, Appleman, James R., Erion, Mark D.

Journal:

Journal of Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 332 KB

english, 2000

2

Behavioral, Physiological and Biochemical Responses of Goats to Temperature, 0° to 40° C.

Appleman, Robert D., Delouche, James C.

Journal:

Journal of Animal Science

Year:

1958

Language:

english

File:

PDF, 523 KB

english, 1958

3

Transcription inactivation through local refolding of the RNA polymerase structure

Belogurov, Georgiy A., Vassylyeva, Marina N., Sevostyanova, Anastasiya, Appleman, James R., Xiang, Alan X., Lira, Ricardo, Webber, Stephen E., Klyuyev, Sergiy, Nudler, Evgeny, Artsimovitch, Irina

Journal:

Year:

2008

Language:

english

File:

PDF, 566 KB

english, 2008

4

Mouse embryo fibroblasts transformed by activated ras or dominant-negative p53 express cross-reactive tumor rejection antigens

Leonard J. Appleman, James Uyeki, Alan B. Frey

Journal:

International Journal of Cancer

Year:

1995

Language:

english

File:

PDF, 929 KB

english, 1995

5

Kinetic Scheme for Thymidylate Synthase from Escherichia coli : Determination from Measurements of Ligand Binding, Primary and Secondary Isotope Effects, and Pre-Steady-State Catalysis †

Spencer, H. Trent, Villafranca, J. Ernest, Appleman, James R.

Journal:

Year:

1997

Language:

english

File:

PDF, 463 KB

english, 1997

6

Native American Student Participation in Study Abroad: An Exploratory Case Study

Wanger, Stephen, Minthorn, Robin, Weinland, Kathryn, Appleman, Boomer, James, Michael, Arnold, Allen

Journal:

American Indian Culture and Research Journal

Year:

2012

Language:

english

File:

PDF, 339 KB

english, 2012

7

Pediatric SARS-CoV-2: Clinical Presentation, Infectivity, and Immune Responses

Yonker, Lael M., Neilan, Anne M., Bartsch, Yannic, Patel, Ankit B., Regan, James, Arya, Puneeta, Gootkind, Elizabeth, Park, Grace, Hardcastle, Margot, St. John, Anita, Appleman, Lori, Chiu, Michelle L

Journal:

The Journal of Pediatrics

Year:

2020

File:

PDF, 1.39 MB

2020

8

In Vitro Combination of ANA598 with Other Anti-HCV Agents can Eliminate the Emergence of Resistant Colonies

Peggy Thompson, Richard Showalter, Rupal Patel, James Appleman

Journal:

Antiviral Research

Year:

2010

Language:

english

File:

PDF, 72 KB

english, 2010

9

Role of lysine-54 in determining cofactor specificity and binding in human dihydrofolate reductase

Huang, Shaoming, Appleman, James R., Tan, Xuehai, Thompson, Paul D., Blakley, Raymond L., Sheridan, Robert P., Venkataraghavan, Rengachari, Freisheim, James H.

Journal:

Year:

1990

Language:

english

File:

PDF, 2.15 MB

english, 1990

10

Discovery of AMP Mimetics that Exhibit High Inhibitory Potency and Specificity for AMP Deaminase

Erion, Mark D., Kasibhatla, Srinivas Rao, Bookser, Brett C., van Poelje, Paul D., Reddy, M. Rami, Gruber, Harry E., Appleman, James R.

Journal:

Journal of the American Chemical Society

Year:

1999

Language:

english

File:

PDF, 262 KB

english, 1999

11

Engineering a chemical implementation device and an imaging device for detecting chemiluminescence with a Polaroid™ high-speed detector film: application to influenza diagnostics with the ZstatFlu®-II test

Komandoor E. Achyuthan, Lisa M. Pence, Daniel R. Mantell, Paul E. Nangeroni, Donald M. Mauchan, William M. Aitken, James R. Appleman, Craig D. Shimasaki

Journal:

Year:

2003

Language:

english

File:

PDF, 258 KB

english, 2003

12

Identification of Ligand Binding by Protein Stabilization: Comparison of ATLAS with Biophysical and Enzymatic Methods

Thompson, Peggy A., Wang, Shaohui, Howett, Lindsay J., Wang, Mei-Mei, Patel, Rupal, Averill, April, Showalter, Richard E., Li, Bin, Appleman, James R.

Journal:

Assay and Drug Development Technologies

Year:

2008

Language:

english

File:

PDF, 434 KB

english, 2008

13

Phase I clinical trial of bortezomib in combination with gemcitabine in patients with advanced solid tumors

David P. Ryan, Leonard J. Appleman, Thomas Lynch, Jeffrey G. Supko, Panagiotis Fidias, Jeffrey W. Clark, Mayer Fishman, Andrew X. Zhu, Peter C. Enzinger, Oscar Kashala, James Cusack Jr., Joseph P. Ede

Journal:

Year:

2006

Language:

english

File:

PDF, 114 KB

english, 2006

14

Radium-223 Therapy for Patients with Metastatic Castrate-Resistant Prostate Cancer: An Update on Literature with Case Presentation

Nguyen, Nghi C., Shah, Muhammad, Appleman, Leonard J., Parikh, Rahul, Mountz, James M.

Journal:

International Journal of Molecular Imaging

Year:

2016

Language:

english

File:

PDF, 2.64 MB

english, 2016

15

Myxopyronin B analogs as inhibitors of RNA polymerase, synthesis and biological evaluation

Thomas Doundoulakis, Alan X. Xiang, Ricardo Lira, Konstantinos A. Agrios, Stephen E. Webber, Wes Sisson, Robert M. Aust, Amit M. Shah, Richard E. Showalter, James R. Appleman, Klaus B. Simonsen

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 330 KB

english, 2004

16

Bone Deficits in Parenteral Nutrition–Dependent Infants and Children With Intestinal Failure Are Attenuated When Accounting for Slower Growth

Appleman, Stephanie S., Kalkwarf, Heidi J., Dwivedi, Alok, Heubi, James E.

Journal:

Journal of Pediatric Gastroenterology & Nutrition

Year:

2013

Language:

english

File:

PDF, 396 KB

english, 2013

17

ZstatFlu®-II test: a chemiluminescent neuraminidase assay for influenza viral diagnostics

Komandoor E. Achyuthan, Lisa M. Pence, James R. Appleman, Craig D. Shimasaki

Journal:

Year:

2003

Language:

english

File:

PDF, 113 KB

english, 2003

18

In Vitro Combination Studies of ANA598 with Anti-HCV Agents Demonstrate Enhanced Anti-viral Activity

Rupal Patel, Peggy Thompson, Richard Showalter, James Appleman

Journal:

Antiviral Research

Year:

2010

Language:

english

File:

PDF, 88 KB

english, 2010

19

ATLAS—A High-Throughput Affinity-Based Screening Technology for Soluble Proteins: Technology Application Using p38 MAP Kinase

Patel, Rupal, LeBrun, Laurie A., Wang, Shaohui, Howett, Lindsay J., Thompson, Peggy A., Appleman, James R., Li, Bin

Journal:

Assay and Drug Development Technologies

Year:

2008

Language:

english

File:

PDF, 1.21 MB

english, 2008

20

Design, Synthesis and Anticonvulsant Activity of the Potent Adenosine Kinase Inhibitor GP3269

Erion, Mark D., Ugarkar, Bheemarao G., DaRe, Jay, Castellino, Angelo J., Fujitaki, James M., Dixon, Ross, Appleman, James R., Wiesner, James B.

Journal:

Nucleosides and Nucleotides

Year:

1997

Language:

english

File:

PDF, 441 KB

english, 1997

21

Techniques in Protein Chemistry III || AN IMPROVED STRATEGY FOR THE DETERMINATION OF THE ROLE IN CATALYSIS OF AMINO ACID RESIDUES IN THYMIDYLATE SYNTHASE11This work was supported in part by United States Public Health Service Research Grant R29 GM 45367 (to JRA) and by American Lebanese Syrian Associated Charities (JRA)

Appleman, James R.

Year:

1992

File:

PDF, 861 KB

1992

22

The therapeutic potential of agents acting via purine receptors

Appleman, James R, Erion, Mark D

Journal:

Expert Opinion on Investigational Drugs

Year:

1998

Language:

english

File:

PDF, 338 KB

english, 1998

23

Kinetics of the purified glucose transporter. Direct measurement of the rates of interconversion of transporter conformers

Appleman, James R., Lienhard, Gustav E.

Journal:

Year:

1989

Language:

english

File:

PDF, 848 KB

english, 1989

24

Apparent stability constants of H+ and Mg2+ complexes of 5-phosphoribosyl α-1-pyrophosphate

Richard E. Thompson, Edwin L.-F. Li, H. Olin Spivey, John P. Chandler, Alan J. Katz, James R. Appleman

Journal:

Bioinorganic Chemistry

Year:

1978

Language:

english

File:

PDF, 762 KB

english, 1978

25

Critical Role of Phenylalanine 34 of Human Dihydrofolate Reductase in Substrate and Inhibitor Binding and in Catalysis

Nakano, Takayuki, Spencer, H. Trent, Appleman, James R., Blakley, Raymond L.

Journal:

Year:

1994

Language:

english

File:

PDF, 1013 KB

english, 1994

26

Mobility of the spin-labeled side chains of some novel antifolate inhibitors in their complexes with dihydrofolate reductase

Raymond L. BLAKLEY, James R. PIPER, Geeta MAHARAJ, James R. APPLEMAN, Tavner J. DELCAMP, James H. FREISHEIM, Robert F. KULINSKI, John A. MONTGOMERY

Journal:

Year:

1991

Language:

english

File:

PDF, 1.15 MB

english, 1991

27

Carcinoma of the oral cavity and jaws

Harold F. Schuknecht, Joseph H. Leek, Robert M. Appleman, James R. Blayney

Journal:

Oral Surgery, Oral Medicine, Oral Pathology

Year:

1953

Language:

english

File:

PDF, 8.86 MB

english, 1953

28

AMP Deaminase Inhibitors. 2. Initial Discovery of a Non-Nucleotide Transition-State Inhibitor Series 1

Bookser, Brett C., Kasibhatla, Srinivas Rao, Appleman, James R., Erion, Mark D.

Journal:

Journal of Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 424 KB

english, 2000

29

Calcium carbonate does not affect imatinib pharmacokinetics in healthy volunteers

Tawbi, Hussein, Christner, Susan M., Lin, Yan, Johnson, Matthew, Mowrey, Emily T., Cherrin, Craig, Chu, Edward, Lee, James J., Puhalla, Shannon, Stoller, Ronald, Appleman, Leonard R., Miller, Brian M.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2014

Language:

english

File:

PDF, 212 KB

english, 2014

30

Dissociation constants for dihydrofolic acid and dihydrobiopterin and implications for mechanistic models for dihydrofolate reductase

Maharaj, Geeta, Selinsky, Barry S., Appleman, James R., Perlman, Michael, London, Robert E., Blakley, Raymond L.

Journal:

Year:

1990

Language:

english

File:

PDF, 910 KB

english, 1990

31

ECOG-ACRIN (E4805) Randomized Phase II Study to Determine the Effect of 2 Different Doses of Aflibercept in Patients with Metastatic Renal Cell Carcinoma

Pili, Roberto, Jegede, Opeyemi, Carducci, Michael A., Manola, Judith, Groteluschen, David L., Appleman, Leonard L., Liu, Glenn, Shanks, James C., Dakhil, Shaker R., Dutcher, Janice, DiPaola, Robert S.

Journal:

Clinical Genitourinary Cancer

Year:

2017

Language:

english

File:

PDF, 1.19 MB

english, 2017

32

ChemInform Abstract: AMP Deaminase Inhibitors. Part 2. Initial Discovery of a Non-Nucleotide Transition-State Inhibitor Series.

Brett C. Bookser, Srinivas Rao Kasibhatla, James R. Appleman, Mark D. Erion

Journal:

Year:

2000

File:

PDF, 32 KB

2000

33

A Phase I study of bortezomib plus irinotecan in patients with advanced solid tumors

David P. Ryan, Bert H. O'Neil, Jeffrey G. Supko, Carlo M. Rocha Lima, E. Claire Dees, Leonard J. Appleman, Jeffrey Clark, Phinos Fidias, Robert Z. Orlowski, Oscar Kashala, Joseph P. Eder, James C. Cus

Journal:

Year:

2006

Language:

english

File:

PDF, 278 KB

english, 2006

34

Titration of histidine 62 in R67 dihydrofolate reductase is linked to a tetramer .tautm. two-dimer equilibrium

Nichols, Robert, Weaver, C. David, Eisenstein, Edward, Blakley, Raymond L., Appleman, James, Huang, Tai Huang, Huang, Fu Yung, Howell, Elizabeth E.

Journal:

Year:

1993

Language:

english

File:

PDF, 1.97 MB

english, 1993

35

Effect of enzyme and ligand protonation on the binding of folates to recombinant human dihydrofolate reductase: implications for the evolution of eukaryotic enzyme efficiency

Appleman, James R., Tsay, Jiu Tsair, Freisheim, James H., Blakley, Raymond L.

Journal:

Year:

1992

Language:

english

File:

PDF, 850 KB

english, 1992

36

New point of care test is highly specific but less sensitive for influenza virus A and B in children and adults

William D. Rawlinson, Zubair M. Waliuzzaman, Michael Fennell, James R. Appleman, Craig D. Shimasaki, Ian W. Carter

Journal:

Journal of Medical Virology

Year:

2004

Language:

english

File:

PDF, 72 KB

english, 2004

37

Kinetic investigation of the functional role of phenylalanine-31 of recombinant human dihydrofolate reductase

Tsay, Jiu Tsair, Appleman, James R., Beard, William A., Prendergast, Neal J., Delcamp, Tavner J., Freisheim, James H., Blakley, Raymond L.

Journal:

Year:

1990

Language:

english

File:

PDF, 1.11 MB

english, 1990

38

A novel inhibitor of respiratory syncytial virus isolated from ethnobotanicals

Joshua O. Ojwang, Yan-Hong Wang, Philip R. Wyde, Nikolaus H. Fischer, Wolfgang Schuehly, James R. Appleman, Soreeta Hinds, Craig D. Shimasaki

Journal:

Antiviral Research

Year:

2005

Language:

english

File:

PDF, 333 KB

english, 2005

39

Effects of conversion of phenylalanine-31 to leucine on the function of human dihydrofolate reductase

Prendergast, Neal J., Appleman, James R., Delcamp, Tavner J., Blakley, Raymond L., Freisheim, James H.

Journal:

Year:

1989

Language:

english

File:

PDF, 788 KB

english, 1989

40

ChemInform Abstract: AMP Deaminase Inhibitors. Part 3. SAR of 3-(Carboxyarylalkyl)coformycin Aglycon Analogues.

Srinivas Rao Kasibhatla, Brett C. Bookser, Gary Probst, James R. Appleman, Mark D. Erion

Journal:

Year:

2000

Language:

english

File:

PDF, 34 KB

english, 2000

41

Role of the conserved active site residue tryptophan-24 of human dihydrofolate reductase as revealed by mutagenesis

Beard, William A., Appleman, James R., Huang, Shaoming, Delcamp, Tavner J., Freisheim, James H., Blakley, Raymond L.

Journal:

Year:

1991

Language:

english

File:

PDF, 1.60 MB

english, 1991

42

Pharmacokinetics and Pharmacodynamics of Setrobuvir, an Orally Administered Hepatitis C Virus Non-Nucleoside Analogue Inhibitor

Mallalieu, Navita L., Rahimy, Mohamad H., Crowley, Constance A., Appleman, James R., Smith, Patrick F., Freddo, James L.

Journal:

Clinical Therapeutics

Year:

2014

Language:

english

File:

PDF, 580 KB

english, 2014

43

Desorption of carboxylates and phosphonates from galvanized steel: Towards greener lubricants

Hill, Donald, Holliman, Peter J., Jones, Eurig W., McGettrick, James, Worsley, David A., Appleman, Marco, Chatterjee, Pranesh

Journal:

Surface and Interface Analysis

Year:

2019

Language:

english

File:

PDF, 1.35 MB

english, 2019

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